Pharmaceuticals ->
Cilostazol
Cilostazol tablet
General Name: cilostazol
Chemical Name: 6-[4-(1-cyclohexyl -1H-tetrazole -5-sulfuryl )butoxy
]-3,4-dihydro -2(1H)-quinolone
Structural Formula: |
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Molecular Formula : C20H27N5O2
Molecular Weight : 369.47
Properties : white crystal or powder, slightly soluble in carbinol
and ethanol,
insoluble in water
Pharmacological Action: Cilostazol can restrain the activity of
blood platelet and phosphodiesterase in smooth muscle; can resist
blood platelet 's aggregation and hemangiectasis ; can hold back
blood platelet 's aggregation caused by TXA2, but has no effect
to the metabolism of arachidonic acid in blood platelet ; can control
the blood platelet's conglomeration caused by blood platelet conglomeration
inductor ; can reduce the concentration of plasma -thrombus
globulin , blood platelet 4th rhesus factor (PF-4); Can dissociate
the aggregation block.
Cilostazol is a new medicine for treating steady discontinuous
cripple.
Cilostazol quinoline is a type of PDEIII depressor manufactured
by American Otsuka Corporation. It is mainly used to treat steady
intermittent claudication.
Pharmacological action:
Cilostazol is quinoline derivations, which can control the PDEIII
in cells and treat steady discontinuous cripple. Cilostazol and
its metabolic products are CAMP-PDEIII depressor, can control PDEIII
's activity and hold back CAMP degradation and transform in blood
tablets and blood vessels.
Packing : 25kg/Barrel
cas# : 76963-72-1
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